产品货号：
Z28810
中文名称：
TREX2抗体
英文名称：
Anti-TREX2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TREX2 Antibody |
| 指标别名 | three prime repair exonuclease 2;TREX2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | TREX2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | TREX2 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TREX2.The immunogen is located within the last 50 amino acids of TREX2. |
| 计算分子量 | 31kDa |
| 成分 | TREX2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | TREX2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | TREX2 is one of two major human 3' to 5' exonucleases which are required for checkpoint signaling after DNA damage.While the related protein TREX1 is required for ATR expression and mutations in this gene result in Aicardi-Goutieres syndrome,chilblain lupus,and Cree encephalitis,less is known about TREX2.Like TREX1,TREX2 is ubiquitously expressed in all tissues examined.X-ray crystallography studies of TREX2-single strand DNA complexes revealed that TREX2 binds DNA as a dimer and may act to displace the second DNA strand,suggesting that TREX2 unzips and denatures double stranded DNA and feed the substrate DNA strand into the TREX2 active site.At least two isoforms of TREX2 are known to exist. |
| Uniprot ID | Q9BQ50 |
| 基因名全称 | Three prime repair exonuclease 2 |
| 蛋白名全称 | Three prime repair exonuclease 2 |
| 推荐稀释比 | TREX2 antibody can be used for detection of TREX2 by Western blot at 2.5μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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